Predicted HIV-1 Drug Resistance in a Pre-treated Population in Northern South Africa

South Africa introduced the diagnose and treat universal HIV treatment programme in September 2016. This program enables all identified HIV positive patients to immediately start first line antiretroviral treatment. However, transmission of drug resistant viruses complicates the choice of antiretroviral treatment. We used next generation sequencing to determine the prevalence and diversity of HIV drug resistance mutations in patients entering HIV treatment programmes in northern South Africa.