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Myc-dependent purine biosynthesis regulates the expression of oncogenes and tumour suppressors in prostate cancer cells

ChEBI2016-03-17 更新2026-07-12 收录

癌细胞重编程

前列腺癌分子机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-51384 数据链接链接失效反馈

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资源简介：

Myc-dependent purine biosynthesis regulates the expression of oncogenes and tumour suppressors in prostate cancer cells

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创建时间：

2016-03-17

前列腺癌分子机制

基因表达调控

The goals of this study is to find effect of overexpression-TFEB in prostate cancer cell (DU145 cell line). Overall design: To further explore the potential molecular mechanisms of how TFEN affects ca

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Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

NIAID Data Ecosystem60

RNAseq PC3 DMSO vs GW3965. RNAseq PC3 DMSO vs GW3965

前列腺癌分子机制

单细胞RNA测序药物研究

Identify LXR target gens that are involved in migration and invasion phenotype Overall design: PC3 prostate cancer cell were treated for 24h with DMSO or GW3965 1µM in RPMI-1640, L-Glu 2mM after overn

NIAID Data Ecosystem10

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

前列腺癌分子机制

激素受体功能

Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants

NIAID Data Ecosystem60

Circular RNA hsa_circ_0075542 acts as a sponge for microRNA-1197 to suppress malignant characteristics and promote apoptosis in prostate cancer cells

前列腺癌分子机制

环状RNA功能研究

Numerous differentially expressed circular RNAs (circRNAs) have been identified; however, their roles have not been fully elucidated. Since dysregulated circRNAs may have clinical applications, it is

Taylor & Francis Group2024-02-20 更新10

Myc-dependent purine biosynthesis regulates the expression of oncogenes and tumour suppressors in prostate cancer cells

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