Aminoimidazoles as BACE-1 Inhibitors: From De Novo Design to Ab- lowering in Brain
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https://pdbj.org/mine/summary/4b78
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Aminoimidazoles as BACE-1 Inhibitors: From De Novo Design to Ab- lowering in Brain Descriptor: (3R,5R)-3-methoxy-5-(4-methoxyphenyl)-5-(3-pyridin-3-ylphenyl)-3,4-dihydropyrrol-2-amine, BETA-SECRETASE 1 Authors: Gravenfors, Y, Blid, J, Ginman, T, Karlstrom, S, Kihlstrom, J, Kolmodin, K, Lindstrom, J, Berg, S, Kieseritzky, F, Slivo, C, Swahn, B, Viklund, J, Olsson, L, Johansson, P, Eketjall, S, Falting, J, Jeppsson, F, Stromberg, K, Janson, J, Rahm, F. Deposit date: 2012-08-16 Release date: 2013-06-26 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Core Refinement Toward Permeable Beta-Secretase (Bace-1) Inhibitors with Low Herg Activity. J.Med.Chem., 56, 2013
创建时间：
2012-08-16
