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Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

ChEBI2010-03-05 更新2026-07-21 收录

巨噬细胞免疫调节

炎症基因增强子识别

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-19553 数据链接链接失效反馈

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资源简介：

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

应用场景：

创建时间：

2010-03-05

动脉粥样硬化机制

巨噬细胞免疫调节

BackgroundAtherosclerosis (AS) remains a leading cause of cardiovascular morbidity and mortality, characterized by intricate interactions between immune dysregulation and lipid metabolism abnormalitie

NIAID Data Ecosystem70

The Role of Non-Conserved Long Noncoding RNA, RP11-184M15.1, in Human Macrophage Function. The Role of Non-Conserved Long Noncoding RNA, RP11-184M15.1, in Human Macrophage Function

非编码RNA功能

巨噬细胞免疫调节

Through deep RNA-seq of human monocyte-derived macrophages, we identified RP11-184M15.1, a human macrophage-specific lincRNA, to be highly induced in the cytoplasm of IL-4-stimulated macrophage. Preli

NIAID Data Ecosystem40

Supplementary Material for: Regulation of macrophage cell surface GAPDH alters LL-37 internalization and downstream effects in the cell

宿主防御肽内化机制

巨噬细胞免疫调节

Mycobacterium tuberculosis (M.tb), the major causative agent of tuberculosis (TB), has evolved mechanisms to evade host defenses and persist within host cells. Host directed therapies (HDTs) against i

NIAID Data Ecosystem20

Bmal1 regulates inflammatory response in macrophage

巨噬细胞免疫调节

表观遗传时序分析

Deletion of Arntl disrupted temporal inflammatory response in macrophage. Mechanistically, the acetylation status of lysine 27 of histone 3 (H3K27ac) was enhanced at the PU.1-containing enhancers in A

NIAID Data Ecosystem60

Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa

免疫转录组

巨噬细胞免疫调节

The ability of bacteriophages to kill bacteria is well known, as is their potential use as alternatives to antibiotics. As such, bacteriophages reach high doses locally through infection of their bact

NIAID Data Ecosystem30

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

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