In the present study, miRNome profiling was carried out to investigate the microRNA expression patterns of multiple myeloma patients and to assess the pathogenetic role of differentially expressed miR
The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,
Aberrant activation of embryonic signaling pathways is frequent in pancreatic ductal adenocarcinoma (PDA) making developmental regulators therapeutically attractive. Here, we demonstrate diverse funct
Additional file 3. Overexpression of ALKBH5 decreased the proliferation capacity in 2 HCC cell lines, while co-overexpressed of PAQR4 reverted this phenomenon (A and B). Overexpression of ALKBH5 decre
Functional annotation clustering of genes with a H3K27ac differently enriched promoter connected to transcription factors with motifs overrepresented in soleus and EDL myonuclei, respectively. Cluster