These files contain next-generation sequencing data (sequencer: Ion Torrent PGM) aligned to hg19 genome used to produce the data presented in figure 2A of the manuscript.
BackgroundThe co-inhibitory receptor Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) attenuates immune responses and prevent autoimmunity, however, tumors exploit this pathway to evade the host T-cell respo
Regional mutation density (RMD) signatures obtained after appling NMF into a matrix of mutation density across 1Mb windows along the genome for 4221 tumor samples. The values provided (NMF exposures)