Dataset supporting the University of Southampton Doctoral Thesis " Engineering glycosylation in HIV-1 vaccine design"

Dataset supporting the University of Southampton Doctoral Thesis " Engineering glycosylation in HIV-1 vaccine design". Data comprises excel spreadsheets for site-specific glycan analysis contained within the thesis.

Zipped folder containing excel files contianing data pertaining to chapters:
- Chapter 3 data.xlsx: All data associated with Chapter 3
- chapter 4 data.xlsx: All data associated with Chapter 4
- Chapter 5 data.xlsx: All data associated with Chapter 5
- Chapter 6 data.xlsx: All data associated with Chapter 6

Publications associated with these datasets include:
-G. E.Seabright et al “Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions” Structure(2020).issn:18784186.doi:10.1016/j.str.2020.04.022.

-E. T Crooks et al “Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine
regimens”, PLOS Pathogens(2021). doi:10.1371/journal.ppat.1009807

-T. Tong et al ”Impact of stabilizing mutations on the antigenic profile and glycosylation of membrane-expressed HIV-1 envelope glycoprotein”, PLOS Pathogens(2023). doi:10.1371/journal.ppat.1011452

This project has received funding from the European Union's Horizon 2020 Research and Innovation program under grant agreement no. 681137, the Bill and Melinda Gates Foundation through the Collaboration for AIDS Vaccine Discovery (OPP1084519 and OPP1115782)