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Tranmission electron micrograph of a representative untreated sac1∆ mutant cell. SAC1 encodes a phosphatase that converts phosphatidylinositol 4-phosphate (PIP) to phosphatidylinositol (PI). sac1∆ mutant cells have fewer normal vacuoles than wildtype. (10,000X). An image of the same mutant treated with sertraline is available as CIL 40433.

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2013-03-09
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