HUMAN PRMT5:MEP50 COMPLEX IN COMPLEX WITH LIGAND 18
收藏Protein Data Bank Japan2025-12-10 更新2026-04-19 收录
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HUMAN PRMT5:MEP50 COMPLEX IN COMPLEX WITH LIGAND 18 Descriptor: (1S,2R,3S,5R)-3-{2-[2-amino-6-(2-hydroxyethyl)quinolin-7-yl]ethyl}-5-(7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol, 1,2-ETHANEDIOL, GLYCEROL, ... Authors: Milligan, C. Deposit date: 2025-06-27 Release date: 2025-09-10 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli. J.Med.Chem., 68, 2025
创建时间：
2025-06-27
