Analysis of Lsm protein-mediated regulation in the haloarchaeon Haloferax mediterranei

The transcriptional analysis of the HM26-ΔSm1 deletion mutant versus the parental strain HM26 was performed under nitrogen and carbon starvation for 120 h. These contrasts allow us to analyze the effect that the deletion of the Sm1 motif has under these conditions and, therefore, allow us to know which genes are regulated by the Lsm protein under the conditions analyzed. Four-condition experiments with four biological replicates, combined in a loop design.