Molecularly targeted optical contrast agents have the potential to enable surgeons to visualize specific molecular markers that can help improve surgical precision and thus outcomes. Fluorescently que
The limited depth penetration of light in tissue, caused by absorption and multiple scattering, is a major challenge for its use in diagnostics and treatment in vivo. To overcome this limitation, we h
A novel multispectral imaging instrument was developed, which integrated visible and NIR-Ι/II wavelengths. The advantages of NIR-II fluorescence were investigated in liver tumour surgical guidance. Th
This study evaluates the safety and performance of SGM-101, a Carcinoembryonic Antigen (CEA)-specific chimeric antibody conjugated with a NIR emitting fluorochrome, for the visualization of CEA-expres