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H3K27me3 maintains the transcription program during epigenetic reprogramming in the mouse germ line [RNA-seq D4]. H3K27me3 maintains the transcription program during epigenetic reprogramming in the mouse germ line [RNA-seq D4]

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NIAID Data Ecosystem2026-03-12 收录
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To investigate the role of EZH2 in transcription regulation in mouse primordial germ cell like cells (PGCLCs), we isolated Ctrl and Ezh2 KO PGCLCs. Our data demonstrates that EZH2-mediated H3K27me3 is dispensible for transcription regulation in PGCLCs. Overall design: Gene expression profiles of Ctrl and Ezh2 KO PGCLCs at PGCLC 4 days of induction.

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2020-12-16
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