Synthesis of (−)-Homogalanthamine from Naltrexone
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Synthesis_of_Homogalanthamine_from_Naltrexone/2672449
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资源简介:
Acetylcholinesterase inhibitor (−)-homogalanthamine 3 was synthesized from μ opioid antagonist naltrexone (2) in 16% total yield. The synthesis features Grob fragmentation as a key reaction, which was especially accelerated in the presence of 15-crown-5.
创建时间:
2016-02-23



