Thyroid function in causal relation to MRI markers of cerebral small vessel disease: a Mendelian randomization analysis

The supplementary data of a article titled " <strong>Thyroid function in causal relation to MRI markers of cerebral small vessel disease: a Mendelian randomization analysis</strong> " <br> <strong>Overview of supplementary tables</strong> Table S1. Summary-level instrument-TSH associations Table S2. Summary-level instrument-FT4 associations Table S3. Summary-level instrument-hypo and hyperthyroidism associations Table S4. Sensitivity analyses of mendelian randomization for the association of thyroid function with CSVD using adverse approaches Table S5. Sensitivity analyses of mendelian randomization for the association of thyroid function with CSVD using multivariable inverse-variance weighted approach Table S6. Mendelian randomization pleiotropy and heterogeneity analyses for the association of thyroid function with CSVD <br> <strong>Overview of supplementary figures</strong> Figure S1. Scatter plots for MR analyses of the associations of stratified TSH levels with the risk of cerebral small vessel disease Figure S2. Scatter plots for MR analyses of the associations of stratified FT4 levels with the risk of cerebral small vessel disease Figure S3. Scatter plots for MR analyses of the associations of hypo and hyperthyroidism with the risk of cerebral small vessel disease Figure S4. MR leave-one-out sensitivity analysis for the associations of thyroid function with the risk of cerebral small vessel disease Figure S5. MR leave-one-out sensitivity analysis for the associations of stratified TSH levels with the risk of cerebral small vessel disease Figure S6. MR leave-one-out sensitivity analysis for the associations of stratified FT4 levels with the risk of cerebral small vessel disease Figure S7. MR leave-one-out sensitivity analysis for the associations of hypo and hyperthyroidism with the risk of cerebral small vessel disease Figure S8. Funnel plots for MR analyses of the associations of thyroid function with the risk of cerebral small vessel disease Figure S9. Funnel plots for MR analyses of the associations of stratified TSH levels with the risk of cerebral small vessel disease Figure S10. Funnel plots for MR analyses of the associations of stratified FT4 levels with the risk of cerebral small vessel disease Figure S11. Funnel plots for MR analyses of the associations of hypo and hyperthyroidism with the risk of cerebral small vessel disease