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Transcriptome analysis of in vitro endotoxin tolerant human monocytes

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE15219
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Monocyte exposure to lipopolysaccharide (LPS) induces a transient state in which these cells are refractory to further endotoxin stimulation. Here we demonstrate the transcriptome analysis of in vitro generated LPS refractory monocytes upon subsequent re-exposure to LPS for different time points. Total RNA obtained from human monocyte exposure treated with LPS for 3h, 6h, or 24h, subsequent to endotoxin tolerization or not.
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2012-03-21
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