Intratracheal LD50 Doses of Francisella Strains in Fischer 344 Rats.
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Groups of Fischer 344 rats (n = 6) were challenged intratracheally with increasing doses (102 to 107 CFU) of subsp. novicida strain U112, subsp. holarctica strain LVS, subsp. holarctica strain OR96-0246, or subsp. tularensis strain SCHU S4 and monitored daily for morbidity and mortality and the LD50 and mean time to death (MTD) calculated. Results for each strain are representative of at least two separate experiments.
创建时间：
2015-12-02
