Animal models.

NIAID Data Ecosystem2026-03-07 收录

基因敲除模型

疾病机制研究

数据链接：

https://figshare.com/articles/dataset/_Animal_models_/239944 数据链接链接失效反馈

官方服务：

资源简介：

SD – Sprague Dawley; ApoE−/− – Apolipoprotein E; GzmB−/− – Granzyme B (B6.129S2–Gzmbtm1Ley/J); PAI-1−/− – Plasminogen Activator Inhibitor-1 (B6.129S2-Serpine1tm1Mlg).

创建时间：

2012-09-26

Single-cell multiomics study of cell-type-specific neuron activation unravels context-dependent gene regulation of brain disorders

单细胞多组学

疾病机制研究

Genome-wide association studies (GWAS) have identified many risk genes for neuropsychiatric disorders (NPD) such as schizophrenia (SCZ). However, functional interpretation of these GWAS findings remai

NIAID Data Ecosystem80

Transcriptome profiling of murine aortic Vascular Smooth Muscle cells from ApoE knockout and ApoE/Neil3 double knockout mice. Transcriptome profiling of murine aortic Vascular Smooth Muscle cells from ApoE knockout and ApoE/Neil3 double knockout mice

平滑肌细胞转录调控

基因敲除模型

We performed high-throughput RNA sequencing to characterize possible differences in the transcriptome of murine aortic Vascular Smooth Muscle cells from both 26 weeks-old ApoE knockout and ApoE/Neil3

NIAID Data Ecosystem50

Serum levels of PGE 2 in wild-type and IVA-PLA 2 -knockout mice.

脂代谢炎症研究

基因敲除模型

Wild-type and IVA-PLA2-knockout (KO) mice were fed normal (N) or high-fat (HF) diets for 16 weeks and fasted. The serum levels of PGE2 were measured (n = 3–5). aP<0.05 versus wild-type mice fed normal

NIAID Data Ecosystem40

Gene expression data from the skin of Cdsniep-/-adult mice. Mus musculus

疾病分子机制

基因敲除模型

Peeling Skin Disease (PSD; OMIM 270300) is an inflammatory ichthyosis due to homozygous loss-of-function mutations in Corneodesmosin (CDSN) and characterized by lifelong patchy peeling of the skin ass

NIAID Data Ecosystem60

DIA quantification proteomics to compare protein expression differences in the hippocampus of wild-type and Mdga2 +/− mice.

神经细胞蛋白质组学

基因敲除模型

DIA quantification proteomics to compare protein expression differences in the hippocampus of wild-type and Mdga2 +/− mice.

Figshare2025-04-01 更新40