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Dataset Ionic liquid supported hydrogel-lipase biocatalytic systems in asymmetric synthesis of enantiomerically pure S-ibuprofen

Zenodo2024-02-05 更新2026-04-07 收录

手性药物合成

酶固定化技术

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https://zenodo.org/doi/10.5281/zenodo.14973972 数据链接链接失效反馈

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This work was supported by the National Science Center, Poland, under research grant no. 2023/49/N/ST8/03038.

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创建时间：

2024-02-05

不对称催化Reissert反应

手性药物合成

The first catalytic enantioselective Reissert reaction of pyridine derivatives that affords products with excellent regio- and enantioselectivity is described. The key for success is the development o

NIAID Data Ecosystem70

Synthesis of a Peroxime Proliferator Activated Receptor (PPAR) α/γ Agonist via Stereocontrolled Williamson Ether Synthesis and Stereospecific S N 2 Reaction of S -2-Chloro Propionic Acid with Phenoxides

手性药物合成

PPARα激动剂

The stereospecific synthesis of the PPAR α/γ agonist 1 was accomplished via ethylation of the optically pure trihydroxy derivative 6, itself derived via an enzymatic resolution. The ethylation can be

NIAID Data Ecosystem40

Spore immobilized enzymes for the multi-step synthesis of cellobiose

生物催化合成

酶固定化技术

Updated data set containing NMR raw data of the final manuscript.

Zenodo2025-12-12 更新30

Enantioselective Michael Additions to α,β-Unsaturated Imides Catalyzed by a Salen−Al Complex

不对称Michael加成

手性药物合成

(Salen)aluminum complex 1b is an efficient catalyst for the conjugate addition of di- and trisubstituted nitriles to a wide range of acyclic alkyl- and aryl-substituted α,β-unsaturated imides. This ne

NIAID Data Ecosystem60

Asymmetric Catalysis upon Helically Chiral Loratadine Analogues Unveils Enantiomer-Dependent Antihistamine Activity

手性药物合成

抗组胺活性研究

Analogues of the conformationally dynamic Claritin (loratadine) and Clarinex (desloratadine) scaffolds have been enantio- and chemoselectively N-oxidized using an aspartic acid containing peptide cata

NIAID Data Ecosystem40

Dataset Ionic liquid supported hydrogel-lipase biocatalytic systems in asymmetric synthesis of enantiomerically pure S-ibuprofen

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