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X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o

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Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10o Descriptor: CARBONATE ION, DIMETHYL SULFOXIDE, N-[(1R)-2-(hydroxyamino)-2-oxo-1-(3',4',5'-trifluorobiphenyl-4-yl)ethyl]-2,2-dimethylpropanamide, ... Authors: Drinkwater, N, McGowan, S. Deposit date: 2015-05-21 Release date: 2016-03-30 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
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2015-05-21
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