Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor
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Crystal structure of spleen tyrosine kinase complexed with an adamantylpyrazine inhibitor Descriptor: 3-amino-6-[3-(1-methyl-1H-pyrazol-4-yl)phenyl]-N-[(1R,2r,3S,5s,7s)-5-hydroxyadamantan-2-yl]pyrazine-2-carboxamide, Tyrosine-protein kinase SYK Authors: Lopez, M, Segarra, V, Vidal, B, Wenzkowski, C, Jestel, A, Krapp, S, Blaesse, M, Nagel, S, Schreiner, P. Deposit date: 2012-01-24 Release date: 2012-04-25 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.48 Å) Cite: Pyrazine-based Syk kinase inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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2012-01-24
