Lactobacillus reuteri normalizes altered fear memory in CNTNAP4 knockout mouse

To explore the function of CNTNAP4 in the regulation of GABAergic transmission, we profiled basolateral amygdala from wild-type and CNTNAP4 knockout female mice by RNA sequencing (RNA-seq). We performed gene expression profiling analysis using data obtained from RNA-seq of WT and CNTNAP4-/- mice为探究接触蛋白相关蛋白4（CNTNAP4）在γ-氨基丁酸能传递（GABAergic transmission）调控中的功能，我们通过RNA测序（RNA-seq）技术，对野生型（wild-type，以下简称WT）与CNTNAP4基因敲除雌性小鼠的基底外侧杏仁核（basolateral amygdala）进行了转录组测序分析。本研究利用WT及CNTNAP4敲除（CNTNAP4-/-）小鼠的RNA-seq数据，完成了基因表达谱分析。