Next Generation Sequencing assesses 53BP1-regulated gene expression profiling in hTRET-RPE1 cells
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https://www.ncbi.nlm.nih.gov/sra/SRP540171
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The goal of this experiment is to analyze global gene expression profiles after depletion of 53BP1 Overall design: hTERT-RPE1 53BP1 knock-out cell line used in this study were generated using CRISPR-Cas9 gene editing approach. Cell were transduced with a lentiviral expression vector encoding a single guide RNAs (gRNAs) against 53BP1, and cells expressing the vector containing only Cas9, but no sgRNA, served as control cell lines.
创建时间:
2025-08-12



