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Crystal structure of deacylation mutant KPC-2 (E166Q)

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of deacylation mutant KPC-2 (E166Q) Descriptor: CHLORIDE ION, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, ... Authors: Tooke, C.L, Hinchliffe, P, Spencer, J. Deposit date: 2020-05-14 Release date: 2020-12-23 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance. J.Biol.Chem., 296, 2020

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2020-05-14
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