Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14d
收藏Protein Data Bank Japan2024-11-20 更新2026-04-19 收录
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Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 14d Descriptor: (1R,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2S)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic acid, (1S,2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]-2-{[N-({[(1R,2S)-2-propylcyclopropyl]methoxy}carbonyl)-L-leucyl]amino}propane-1-sulfonic acid, Orf1a protein, ... Authors: Liu, L, Lovell, S, Battaile, K.P, Nguyen, H.N, Chamandi, S.D, Picard, H.R, Madden, T.K, Thruman, H.A, Kim, Y, Groutas, W.C, Chang, K.O. Deposit date: 2022-01-26 Release date: 2022-03-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacol Transl Sci, 6, 2023
创建时间:
2022-01-26



