Crystal structure of the Neurokinin 1 receptor in complex with the small molecule antagonist CP-99,994

NIAID Data Ecosystem2026-05-02 收录

G蛋白偶联受体分析

药物靶点相互作用

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Crystal structure of the Neurokinin 1 receptor in complex with the small molecule antagonist CP-99,994

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2024-11-06

Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors

G蛋白偶联受体分析

跨膜域选择压力

G protein-coupled receptors (GPCRs) are a superfamily of integral membrane proteins vital for signaling and are important targets for pharmaceutical intervention in humans. Previously, we identified a

NIAID Data Ecosystem100

SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70

G蛋白偶联受体分析

信号传导机制

SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70 Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding p

Protein Data Bank Japan2024-11-13 更新50

Additional file of Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR

神经分子表达

G蛋白偶联受体分析

Additional file of Genome-wide profiling of G protein-coupled receptors in cerebellar granule neurons using high-throughput, real-time PCR

Figshare2021-04-19 更新30

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H7 PROTEIN KINASE INHIBITOR 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE

蛋白激酶抑制剂

药物靶点相互作用

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H7 PROTEIN KINASE INHIBITOR 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE Descriptor: 1-(5-ISOQUINOLINESULFONYL)-2-M

Protein Data Bank Japan2024-10-23 更新50

Structure of EstD11 S144A in complex with naproxen p-nitrophenol ester

酶结构解析

药物靶点相互作用

Structure of EstD11 S144A in complex with naproxen p-nitrophenol ester Descriptor: 4-nitrophenyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate, EstD11 S144A Authors: Miguel-Ruano, V, Rivera, I, Hermoso,

Protein Data Bank Japan2026-04-15 更新50

Crystal structure of the Neurokinin 1 receptor in complex with the small molecule antagonist CP-99,994

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