Evolution_and_adaptation_of_the_epidemic_dysentery_bacterium_Shigella_dysenteriae_type_1__Shiga_s_bacillus__during_the_pre_and_post_antibiotic_era. Evolution_and_adaptation_of_the_epidemic_dysentery_bacterium_Shigella_dysenteriae_type_1__Shiga_s_bacillus__during_the_pre_and_post_antibiotic_era

Comparative genome analysis of the epidemic dysentery bacterium Shigella dysenteriae type 1 (Shiga’s bacillus). Paired-end sequence data has been generated from 264 isolates from epidemics and sporadic cases between 1915 and 2011by using the Illumina Genome Analyzer. PacBio RS paired end sequencing has been also carried out on 10 isolates representing the different genetic lineages and sublineages. These data have been used to correct the genome assembly of Sd197 (CP000034) and improve the knowledge on the population structure, the evolutive history and the transmission dynamics of this pathogen.