E-GEOD-19279

NIAID Data Ecosystem2026-05-02 收录

胰腺导管腺癌转录组学

癌症转移机制

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Transcription profiling by array of normal pancreas, primary pancreatic ductal adenocarcinoma (PDAC), normal liver, and pancreatic liver metastases using the Affymetrix HG-U133A array

创建时间：

2025-01-24

Gene expression profiling of control and Carmil3-deficient 4T1 cells

癌症转移机制

基因表达调控

To systemically study the molecular function of CARMIL3 in cancer cells, we used mammary tumor cells, 4T1, as a model and genetically depleted Carmil3 via CRISPR/Cas9 strategy, followed by genome-wide

NIAID Data Ecosystem50

Flag-RBM47 HITS-CLIP in brain metastatic derivatives of MDA-MB-231

RNA结合蛋白靶标

癌症转移机制

Brain metastatic breast cancer cells were subjected to HITS-CLIP to identify the targets of the RNA binding protein RBM47 MDA231-BrM2a is characterized in PMID: 19421193; Related data published toget

NIAID Data Ecosystem40

TAp63 in pancreas cancer predicts the squamous subtype and promotes a suppressive immune micromilleu

胰腺导管腺癌转录组学

肿瘤免疫微环境

To evaluate the role of aberrant TAp63 in PDAC, we analyzed transcriptomics by RNAseq in the TAp63 and deltaNP63 over-expressing pancreatic cancer cells. A transcriptomic analysis by over-expression o

NIAID Data Ecosystem10

Study of transcriptional changes in MCM7-depleted and G1/S-arrested A549 and A375 cells

癌症转移机制

转录组学分析

We tested if the changes in cell invasion and migration observed after MCM7 depletion manifested in an altered gene expression profile. For this purpose, we performed RNAseq analysis after MCM7 knock-

NIAID Data Ecosystem40

shRNAi profiling of human MDA-MB-231 cells expressing anti-p53 (shp53) short-hairpin RNAs treated with TFGbeta or control

癌症转移机制

转录组功能分析

TGFβ ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers. The molecular nature of this switch remains enigmatic.

NIAID Data Ecosystem30

E-GEOD-19279

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