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Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom.

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Protein Data Bank Japan2025-06-25 更新2026-04-19 收录
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Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom. Descriptor: (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, CHLORIDE ION, Sodium-dependent noradrenaline transporter Authors: Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. Deposit date: 2023-01-18 Release date: 2024-07-03 Last modified: 2025-06-25 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024
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2023-01-18
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