Crystal structure of TFPI K2 domain in complex with TFPI-23 Fab fragment

Crystal structure of TFPI K2 domain in complex with TFPI-23 Fab fragment Descriptor: TFPI-23-Fab Heavy chain, TFPI-23-Fab Light chain, Tissue factor pathway inhibitor Authors: Juo, Z.S, Bard, J, Mosyak, L. Deposit date: 2026-05-18 Release date: 2026-05-27 Last modified: 2026-06-17 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Discovery and optimization of marstacimab, a human monoclonal antibody targeting tissue factor pathway inhibitor for the treatment of hemophilia A and B. Mabs, 18, 2026