Rapid phagosome isolation enables unbiased multiomic analysis of human microglia phagosomes 4

NIAID Data Ecosystem2026-05-02 收录

小胶质细胞吞噬调控

细胞器代谢组学

数据链接：

https://zenodo.org/record/10570144 数据链接链接失效反馈

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资源简介：

Metabolomic data from phagosomes, controls and whole cell fractions of human ex vivo microglia.

创建时间：

2024-08-15

Transcriptomes of ATG7 Knockout Microglia

小胶质细胞吞噬调控

多发性硬化症

Multiple Sclerosis (MS) is a leading cause of incurable progressive disability in young adults caused by inflammation in the central nervous system (CNS) that triggers demyelination, glial cell dysfun

NIAID Data Ecosystem70

Transcriptomes of ATG7 Knockout Microglia

小胶质细胞吞噬调控

多发性硬化症髓鞘清除

NIAID Data Ecosystem50

Local calcium accumulations promote phagocyte-mediated synapse removal in cortical neuroinflammation. Local calcium accumulations promote phagocyte-mediated synapse removal in cortical neuroinflammation

皮质神经炎症突触丢失

小胶质细胞吞噬调控

Cortical pathology contributes to chronic cognitive impairment of patients suffering from the neuroinflammatory disease multiple sclerosis (MS). How such gray matter inflammation affects neuronal stru

NIAID Data Ecosystem30

Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation

阿尔茨海默病分子机制

小胶质细胞吞噬调控

Amyloid-β (Aβ) accumulation in the brain is a hallmark of Alzheimer’s disease (AD) pathology. However, the molecular mechanism controlling microglial Aβ phagocytosis is poorly understood. Here we foun

中国科学院中国科学技术大学科学数据中心60

Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone

小胶质细胞吞噬调控

神经发生微环境

Microglia are the primary phagocytes in the central nervous system and are responsible for clearing dead cells generated during development or disease. The phagocytic process shapes the phenotype of t

NIAID Data Ecosystem40

Rapid phagosome isolation enables unbiased multiomic analysis of human microglia phagosomes 4

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