One-Pot Synthesis of 2‑Cyano-1,4-diketones: Applications to Synthesis of Cyanosubstituted Furans, Pyrroles, and Dihydropyridazines
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https://figshare.com/articles/dataset/One-Pot_Synthesis_of_2_Cyano-1_4-diketones_Applications_to_Synthesis_of_Cyanosubstituted_Furans_Pyrroles_and_Dihydropyridazines/3573654
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资源简介：
A convenient
synthetic route for the construction of functionalized 2-cyano-1,4-diketones
has been established from the nucleophilic substitution of 2-bromoacetophenones
with NaCN via the in situ-generated β-ketonitriles.
This method was further applied to the synthesis of cyanosubstituted
furans, pyrroles, or dihydropyridazines, which were obtained in good
to excellent yields using Bi(OTf)3, NH4OAc,
or N2H4. The key structures were confirmed by
X-ray single crystal diffraction analysis.
创建时间：
2016-08-29
