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C28 Polymerase Incorporating RNA, n+1
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2026-01-21
相关数据集
Nascent elongating transcript sequencing (NET-seq) show different pause registers with apyrase treatment during library preparation
Transcriptional pausing aids gene regulation by cellular RNA polymerases (RNAPs). In many bacteria, a surface-exposed domain inserted into the catalytic trigger loop (TL) of RNAP, called SI3 in Escher
NIAID Data Ecosystem30
Impact of Remdesivir Incorporation along the Primer Strand on SARS-CoV‑2 RNA-Dependent RNA Polymerase
Remdesivir was the first antiviral drug that received emergency use authorization from the United States Food and Drug Administration and is now formally approved to treat COVID-19. Remdesivir is a nu
Figshare2022-04-18 更新30
Hinge action versus grip in translocation by RNA polymerase
Based on molecular dynamics simulations and functional studies, a conformational mechanism is posited for forward translocation by RNA polymerase (RNAP). In a simulation of a ternary elongation comple
Taylor & Francis Group2018-08-01 更新20
The average number of pauses per RNAP, average pause duration, and average pause delay per RNAP due to pauses experienced per RNAP for the different pause frequency functions.
Frequency represents the value of the pause frequency function when torque is 11 pN⋅nm. All of the data reported is for α = 0.0115.
NIAID Data Ecosystem30
Source data files
Source data files for: "Alternative transcription cycle for bacterial RNA polymerase" Timothy T. Harden 1 , Karina S. Herlambang 2† , Mathew Chamberlain 1† , Jean-Benoît Lal
Zenodo2020-10-04 更新20
