A simple spreadsheet for estimating low-effect concentrations and associated confidence intervals with logistic dose response curves

A simple spreadsheet has been developed to estimate low
effect concentrations for continuous responses (e.g. plant weights and
heights). The spreadsheet allows the user to enter data in Excel (a package
with which they familiar). The user enters sensible starting values using
suggestions and interactive graphics, which increases the likelihood of finding
an optimal solution.

The EC of interest is graphically presented along with it’s associated 95% confidence intervals (CIs).

The benefits of this spreadsheet program include:

* Graphical and tabular presentation of results , starting
values and confidence intervals.

* Regularly finds a solution die to graphical interface.

* Wide variety of uses (e.g. bio-availability and toxicity
of metals or pesticides to plants, worms and a range of indicator organisms and aquatic species)

This was presented at SETAC Asia/Pacific Conference, NZ 28/Sep/2003-1/Oct/2003. Requests for the spreadsheet 15 years later continue to encourage the spreadsheet authors.