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Crystal structure of human ClpP protease in complex with TR-65

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Protein Data Bank Japan2023-10-25 更新2026-04-19 收录
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Crystal structure of human ClpP protease in complex with TR-65 Descriptor: 3-{[(10R)-4-[(4-chlorophenyl)methyl]-5-oxo-1,2,4,5,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-7(6H)-yl]methyl}benzonitrile, ATP-dependent Clp protease proteolytic subunit, mitochondrial Authors: Mabanglo, M.F, Houry, W.A. Deposit date: 2022-05-02 Release date: 2023-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure, 31, 2023
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2022-05-02
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