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Macrocyclic Metal Complex–DNA Conjugates for Electrochemical Sensing of Single Nucleobase Changes in DNA

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NIAID Data Ecosystem2026-03-09 收录
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The direct incorporation of macrocyclic cyclidene complexes into DNA via automated synthesis results in a new family of metal-functionalized DNA derivatives that readily demonstrate their utility through the ability of one redox-active copper­(II)-containing strand to distinguish electrochemically between all four canonical DNA nucleobases at a single site within a target sequence of DNA.

创建时间:
2016-02-10
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