Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor

Cryo-EM co-structure of AcrB with the EPM35 efflux pump inhibitor Descriptor: (2S)-1-(3,4-dichlorophenoxy)-3-(4-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}piperidin-1-yl)propan-2-ol, Multidrug efflux pump subunit AcrB Authors: Su, C.C. Deposit date: 2024-04-18 Release date: 2024-05-08 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment. mBio, 14, 2023