Transcriptome profiling for hidradenitis suppurativa. Transcriptome profiling for hidradenitis suppurativa

Hidradenitis Suppurativa (HS) is a debilitating chronic inflammatory disease characterized by chronic abscess formation and development of multiple draining sinus tracts in the groin, axillae, and perineum. Through the use of transcriptomic approaches, we characterize the inflammatory responses in HS in depth, revealing the cell types and immune responses involved. Overall design: We conducted RNA-seq on whole blood and skin obtained from HS patients, and comparing them against control individuals