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Crystal structure of 3C protease of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 84

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal structure of 3C protease of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 84 Descriptor: 3C PROTEINASE, O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonyl-N-{(2R)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl}-L-phenylalaninamide Authors: Tan, J, Anand, K, Mesters, J.R, Hilgenfeld, R. Deposit date: 2011-08-31 Release date: 2012-09-19 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations To be Published
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2011-08-31
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