CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor
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https://pdbj.org/mine/summary/1h00
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CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor Descriptor: (2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2 Authors: Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. Deposit date: 2002-06-10 Release date: 2003-07-11 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
创建时间：
2002-06-10
