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humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186

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Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3fal
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humanRXR alpha & mouse LXR alpha complexed with Retenoic acid and GSK2186 Descriptor: 2-{4-[butyl(3-chloro-4,5-dimethoxybenzyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol, Oxysterols receptor LXR-alpha, RETINOIC ACID, ... Authors: Chao, E.Y, Caravella, J.A, Watson, M.A, Campobasso, N, Ghisletti, S, Billin, A.N, Galardi, C, Willson, T.M, Zuercher, W.J, Collins, J.L. Deposit date: 2008-11-17 Release date: 2009-04-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J.Med.Chem., 51, 2008
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2008-11-17
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