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Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration

NIAID Data Ecosystem2026-03-12 收录

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染色质构型分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE153037 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2021-05-24

环状RNA-蛋白质相互作用

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The exon junction complex (EJC) is a central effector of mRNAs fate, linking nuclear processing to mRNA transport, translation and surveillance. Little is known about its transcriptome-wide targets. W

NIAID Data Ecosystem100

Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

神经发育调控

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During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero le

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Subcellular RNA Sequencing Reveals Broad Presence of Cytoplasmic Intron-sequence Retaining Transcripts in Mouse and Rat Neurons.

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RNA测序

Recent findings have revealed the complexity of the transcriptional landscape in mammalian cells. One recently described class of novel transcripts are the Cytoplasmic Intron-sequence Retaining Transc

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Genome-wide mRNA targets of CPEB1 in muscle stem cells

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肌肉干细胞分子图谱

We performed CPEB1 RIP-seq on freshly isolated muscle stem cells. We found that CPEB1 associated genes are enriched in translational regulation pathways. Overall design: Two biological replicates of C

NIAID Data Ecosystem60

HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA. HuR promotes myogenesis by cooperating with YB-1 to modulate the stability of the Myogenin mRNA

肌生成调控

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Our study delineates a novel mechanism for HuR-mediated posttranscriptional regulation of myogenesis that requires its association to YB1 and provides new insights into the central role of posttranscr

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Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration

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