Genomic drivers shape the glioblastoma microenvironment in de novo genetic mouse models and human tumours — spatial multi-omics dataset

Processed spatial transcriptomic and spatial proteomic data accompanying Kastner et al. The deposit includes 10x Genomics Visium HD (n=4), 10x Genomics Xenium (n=2), and NanoString GeoMx RNA/protein data (n=12) from genetically defined murine glioblastoma models with EGFRvIII expression, Nf1 silencing, or PDGFB overexpression. Samples: Visium HD: 9309A = PDGFB; 9350B = Nf1; 9248A = EGFRvIII; 9259A = EGFRvIII Xenium: 9233A = Nf1; 9248A = EGFRvIII NanoString GeoMx (sample n=12, 4 EGFRvIII expression, 4 Nf1 silencing, 4 PDGFB overexpression)