Genome-wide analysis of PARKIN deficient patient fibroblast and iPSC lines. Homo sapiens

Analysis of whole genome gene expression in control and PARKIN patient lines. The hypothesis tested in the present study was that the deficient of PARKIN expression affects multiple pathways. Results provide important information on relationship between PARKIN and mitochondria related gene expression. Overall design: Total RNA obtained from patient fibroblast and iPSC compare to control fibroblast and iPSC.