Inhibition of muPA wt and muPA exosite mutants by mupain-1 variants.
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The Ki values (in µM) for inhibition of the indicated enzymes by the indicated peptides are shown as means ± S.D; the numbers of determinations are indicated in parentheses. *These values are reproduced from previous publications [Andersen et al., 2008; Hosseini et al., 2011] and shown here to facilitate comparison.
Besides the muPA mutants reported in the table, we found no significant change in Ki values after the following substitutions: Q35A; N37A; K37aA; G37cA; S37dA; P37eA; P38A; Q60aA; E146A; Y149A. For unknown reasons, muPA K192A could not be expressed.
Inhibition of muPA wt and muPA exosite mutants by mupain-1 variants.
创建时间：
2014-12-29
