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Mitochondrial Transfer Rescues Respiration to Support De Novo Pyrimidine Biosynthesis and Tumor Progression

ChEBI2025-10-14 更新2026-07-12 收录

肿瘤代谢重编程

线粒体功能调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-15669 数据链接链接失效反馈

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Mitochondrial Transfer Rescues Respiration to Support De Novo Pyrimidine Biosynthesis and Tumor Progression

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2025-10-14

胰腺癌转录调控

肿瘤代谢重编程

Pancreatic ductal adenocarcinomas (PDACs) are composed of a mixture of highly heterogeneous cancer cells with distinct gene expression programs and functional properties, ranging from well-differentia

NIAID Data Ecosystem60

Table 3_Multiomic analysis of lactylation and mitochondria-related genes in hepatocellular carcinoma identified MRPL3 as a new prognostic biomarker.xlsx

肿瘤代谢重编程

癌症预后生物标志物

BackgroundRecent research has highlighted lactate’s crucial role in epigenetic regulation, particularly by influencing histone modifications that drive the initiation and progression of hepatocellular

NIAID Data Ecosystem40

Carbon Monoxide Improves Cardiac Function and Mitochondrial Population Quality in a Mouse Model of Metabolic Syndrome

疾病治疗

线粒体功能调控

AimsMetabolic syndrome induces cardiac dysfunction associated with mitochondria abnormalities. As low levels of carbon monoxide (CO) may improve myocardial and mitochondrial activities, we tested whet

Figshare2016-01-19 更新40

Additional file 8 of Acetylation-induced degradation of ECHS1 enhances BCAA accumulation and proliferation in KRAS-mutant colorectal cancer

肿瘤代谢重编程

KRAS突变结直肠癌

Supplementary Material 8

Figshare2025-05-28 更新40

PKCα RNA-seq in t(4;14) cells

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PKCα表观遗传调控

Multiple myeloma (MM) cells undergo metabolic reprogramming in response to a hypoxic and nutrient-deprived bone marrow microenvironment. However, it is unclear whether primary oncogenes in recurrent t

NIAID Data Ecosystem40

Mitochondrial Transfer Rescues Respiration to Support De Novo Pyrimidine Biosynthesis and Tumor Progression

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