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Impact of genetic depletion or pharmacological inhibition of LSD1 on gene expression in ovarian cancer cells [ATAC-Seq]

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NIAID Data Ecosystem2026-05-01 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP409836
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资源简介:
LSD1 is frequently overexpressed and correlates with poor prognosis in patients with ovarian cancer. RNA-seq, CUT&Tag-seq and ATAC-seq were performed to determine the impact of genetic depletion or pharmacological inhibition of LSD1 on gene expresion profiles in ovarian cancer cells. Overall design: ATAC-seq was performed in ES2 cells under baseline conditions, treated with 1µM LSD1 inhibitor ZY0511 for 12 h, or treated with shRNA targeting LSD1 (shLSD1).
创建时间:
2023-12-07
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