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Beta cell-specific PAK1 enrichment ameliorates diet-induced glucose intolerance by promoting insulin biogenesis and minimizing beta cell apoptosis

NIAID Data Ecosystem2026-05-02 收录

细胞功能研究

糖尿病分子机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE239382 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-12-27

抗精神病药物代谢

细胞功能研究

Folder 1. Analysis of in vivo chronic dietary treatment with both olanzapine and aripiprazole (5.5-6 mg/kg/d) for 6 months in WT females to assess disturbances in glucose metabolism as well as beta-ce

DataCite Commons2024-10-09 更新50

Disturbance of lipid and glucose metabolism induce beta cell dedifferentiation in Ins-1 cell line

胰岛β细胞

糖尿病分子机制

In this study, we tried to clarify whether abnormal glucose and lipid metabolism can lead to beta cell dedifferentiation in vitro , and whether there is the role of transcription factor Foxo1 in this

NIAID Data Ecosystem30

Table7_PanCircBase: An online resource for the exploration of circular RNAs in pancreatic islets.XLSX

胰腺胰岛

细胞功能研究

Circular RNAs (circRNAs) are a novel class of covalently closed RNA molecules that recently emerged as a critical regulator of gene expression in development and diseases. Recent research has highligh

NIAID Data Ecosystem20

RNA-seq of isolated pancreatic islets from beta-cell-specific Jazf1 knock-out mice

糖尿病分子机制

胰岛β细胞功能基因组学

Genome-wide association studies (GWAS) have identified several susceptibility loci for T2D. Among these loci, juxtaposed with another zinc finger protein 1 gene (JAZF1) has been shown as one of the to

NIAID Data Ecosystem30

RNA-seq of THP-1 cell lines overexpression of MG53

转录组学分析

细胞功能研究

RNA-seq of THP-1 cell lines overexpression of MG53

ChEBI2025-10-30 更新20