Superfamily assignment.

Comparison of our results against earlier classifications by Sidney et al.[28], Hertz and Yanover’s methods [29]; which include both peptide and binding site approaches; Lund et al.[20], and both methods by Doytchinova et al.[24]; which are based on COMSIA (Comparative Similarity Index Analysis) and MIF (Molecular Interaction Fields). ‘-’ denotes that the allele is not included for classification in the particular study. *Superfamily definition based on learned distance function over the binding site of the alleles. ∧Superfamily definition based on peptide-peptide learned distance function.