Examples of genes classified by LitProf- Gene Classifier and further validated by manually reviewing their literature.

*The GO terms from Biological Process, Molecular Function and Cellular Component ontologies associated with each gene in table 4 (or, in most cases, their prokaryotic orthologs) were retrieved from AmiGO (http://amigo.geneontology.org) by querying the database with their canonical gene names. In most cases the GO terms retrieved supported the functional categorization predicted by LitProf – Gene Classifier, although there is not an exact correspondence between GO and JCVI-CMR ontologies. Six gene names out 16 tested had no match in AmiGO.