Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor
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Crystal Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neutrophil elastase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: vonNussbaum, F, Li, V.M, Meibom, D, Anlauf, S, Bechem, M, Delbeck, M, Gerisch, M, Harrenga, A, Karthaus, D, Lang, D, Lustig, K, Mittendorf, J, Schaefer, M, Schaefer, S, Schamberger, J. Deposit date: 2015-07-17 Release date: 2016-08-03 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Potent and Selective Human Neutrophil Elastase Inhibitors with Novel Equatorial Ring Topology: in vivo Efficacy of the Polar Pyrimidopyridazine BAY-8040 in a Pulmonary Arterial Hypertension Rat Model. ChemMedChem, 11, 2016
创建时间：
2015-07-17
